Friday, January 14, 2011

Body Odor Can Increase Breast Cancer Risk

Excessive body odor was touted as one of the factors that can increase the risk of breast cancer. Although the results of research of Japanese scientists is still very early, but this could be a signal for women to better maintain the cleanliness of her.

Japanese scientists recently have discovered a gene variation associated with risk of breast cancer is also associated with body odor and ear wax.

The invention is not intended to create fear of women, said Toshi Ishikawa, PhD, professor of Biomolecular Engineering at Tokyo Institute of Technology. Instead, he said, "we are very hopeful that we will provide new ways to better predict breast cancer risk" using the new method developed by this team.

Have wet earwax or excessive body odor does not mean a woman who has been getting breast cancer, says Ishikawa. "To be clear, I have to explicitly mention that the [discovery of the gene variation associated with body odor, wet earwax, and the risk of breast cancer] is one factor that can increase the risk of breast cancer," says Ishikawa. "It is also closely related to other factors, such as environmental factors and mutations of tumor-like killer gene BRCA1, BRCA2, p53, and so on."

In this study, Ishikawa and his team extracted DNA from blood samples taken from 124 volunteers at the University of Nagasaki Japan.

They studied the ABCC11 gene, which was discovered in 2001. Variations of this gene have been associated with increased risk of breast cancer. These variations are called SNPs ("snips") or single nucleotide polymorphisms, which can happen when a nucleus of a cell or molecular changes. Although many SNPs do not affect the workings of cells, experts believe that sometimes there are variations that can cause a person to certain diseases such as cancer or affect a person's response to treatment.

In this study, Ishikawa observing the activity of proteins made by the gene ABCC11, ABCC11 looking for relationships between genes, body odor and ear wax. Then they discovered the mechanism that regulates cell ear wax, excessive body odor and the risk of breast cancer.

Women Do not Worry

Women do not have to worry with these results, says Christy Russell, MD, professor of the University of Southern California, Los Angeles. "At the moment research is still very early and the women do not need to be concerned over the problem of body odor and dirt ears as a sign that they may have a higher risk of breast cancer."

"The problem of body odor and ear wax is common to everyone" he said.

The researchers are expected to know exactly the level of the cell mechanisms that lead to the three conditions above (body odor, ear wax and breast cancer), said Gerald Weissmann, MD, of The FASEB Journal and a professor of Biotechnology Study Center at New York University.

This is a study that combines the science of genetics, human anthropology, and molecular and cell biology. The development of a rapid method of SNP typing can be used to help predict the risk of serious diseases like cancer by analyzing the things that are considered trivial like body odor and ear wax. "

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